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BMCBI
2005
82views more  BMCBI 2005»
13 years 7 months ago
A novel method for prokaryotic promoter prediction based on DNA stability
Background: In the post-genomic era, correct gene prediction has become one of the biggest challenges in genome annotation. Improved promoter prediction methods can be one step to...
Aditi Kanhere, Manju Bansal
BMCBI
2008
179views more  BMCBI 2008»
13 years 7 months ago
Bayesian modeling of recombination events in bacterial populations
Background: We consider the discovery of recombinant segments jointly with their origins within multilocus DNA sequences from bacteria representing heterogeneous populations of fa...
Pekka Marttinen, Adam Baldwin, William P. Hanage, ...
BMCBI
2005
104views more  BMCBI 2005»
13 years 7 months ago
A statistical approach for array CGH data analysis
Background: Microarray-CGH experiments are used to detect and map chromosomal imbalances, by hybridizing targets of genomic DNA from a test and a reference sample to sequences imm...
Franck Picard, Stéphane Robin, Marc Laviell...
BMCBI
2007
247views more  BMCBI 2007»
13 years 7 months ago
A survey of DNA motif finding algorithms
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
Modan K. Das, Ho-Kwok Dai
ALMOB
2006
80views more  ALMOB 2006»
13 years 7 months ago
Effective p-value computations using Finite Markov Chain Imbedding (FMCI): application to local score and to pattern statistics
The technique of Finite Markov Chain Imbedding (FMCI) is a classical approach to complex combinatorial problems related to sequences. In order to get efficient algorithms, it is k...
Grégory Nuel