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BMCBI
2008
184views more  BMCBI 2008»
13 years 8 months ago
Integrating protein-protein interactions and text mining for protein function prediction
Background: Functional annotation of proteins remains a challenging task. Currently the scientific literature serves as the main source for yet uncurated functional annotations, b...
Samira Jaeger, Sylvain Gaudan, Ulf Leser, Dietrich...
NAR
2011
214views Computer Vision» more  NAR 2011»
12 years 11 months ago
starBase: a database for exploring microRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data
MicroRNAs (miRNAs) represent an important class of small non-coding RNAs (sRNAs) that regulate gene expression by targeting messenger RNAs. However, assigning miRNAs to their regu...
Jian-Hua Yang, Jun-Hao Li, Peng Shao, Hui Zhou, Yu...
ICIC
2009
Springer
14 years 3 months ago
Ensemble Classifiers Based on Kernel PCA for Cancer Data Classification
Now the classification of different tumor types is of great importance in cancer diagnosis and drug discovery. It is more desirable to create an optimal ensemble for data analysis ...
Jin Zhou, Yuqi Pan, Yuehui Chen, Yang Liu
BMCBI
2010
190views more  BMCBI 2010»
13 years 8 months ago
APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Jun-Feng Xia, Xing-Ming Zhao, Jiangning Song, De-S...
BMCBI
2008
117views more  BMCBI 2008»
13 years 8 months ago
A probabilistic framework to predict protein function from interaction data integrated with semantic knowledge
Background: The functional characterization of newly discovered proteins has been a challenge in the post-genomic era. Protein-protein interactions provide insights into the funct...
Young-Rae Cho, Lei Shi, Murali Ramanathan, Aidong ...