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BMCBI
2010
105views more  BMCBI 2010»
13 years 8 months ago
Predicting phenotypic traits of prokaryotes from protein domain frequencies
Background: Establishing the relationship between an organism's genome sequence and its phenotype is a fundamental challenge that remains largely unsolved. Accurately predict...
Thomas Lingner, Stefanie Mühlhausen, Toni Gab...
BMCBI
2006
133views more  BMCBI 2006»
13 years 8 months ago
An integrated approach to the prediction of domain-domain interactions
Background: The development of high-throughput technologies has produced several large scale protein interaction data sets for multiple species, and significant efforts have been ...
Hyunju Lee, Minghua Deng, Fengzhu Sun, Ting Chen
SDM
2009
SIAM
161views Data Mining» more  SDM 2009»
14 years 5 months ago
Feature Weighted SVMs Using Receiver Operating Characteristics.
Support Vector Machines (SVMs) are a leading tool in classification and pattern recognition and the kernel function is one of its most important components. This function is used...
Shaoyi Zhang, M. Maruf Hossain, Md. Rafiul Hassan,...
BMCBI
2010
113views more  BMCBI 2010»
13 years 8 months ago
Improving performance of mammalian microRNA target prediction
Background: MicroRNAs (miRNAs) are single-stranded non-coding RNAs known to regulate a wide range of cellular processes by silencing the gene expression at the protein and/or mRNA...
Hui Liu, Dong Yue, Yidong Chen, Shou-Jiang Gao, Yu...
BMCBI
2007
162views more  BMCBI 2007»
13 years 8 months ago
Genome-wide identification of specific oligonucleotides using artificial neural network and computational genomic analysis
Background: Genome-wide identification of specific oligonucleotides (oligos) is a computationallyintensive task and is a requirement for designing microarray probes, primers, and ...
Chun-Chi Liu, Chin-Chung Lin, Ker-Chau Li, Wen-Shy...