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» Applying Support Vector Machines to Imbalanced Datasets
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BMCBI
2008
169views more  BMCBI 2008»
13 years 7 months ago
A comprehensive comparison of random forests and support vector machines for microarray-based cancer classification
Background: Cancer diagnosis and clinical outcome prediction are among the most important emerging applications of gene expression microarray technology with several molecular sig...
Alexander R. Statnikov, Lily Wang, Constantin F. A...
BMCBI
2007
127views more  BMCBI 2007»
13 years 7 months ago
Predicting the phenotypic effects of non-synonymous single nucleotide polymorphisms based on support vector machines
Background: Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occur approximately every 1000 bases in the overall human population. The no...
Jian Tian, Ningfeng Wu, Xuexia Guo, Jun Guo, Juhua...
ESWA
2007
127views more  ESWA 2007»
13 years 7 months ago
Clustering support vector machines for protein local structure prediction
Understanding the sequence-to-structure relationship is a central task in bioinformatics research. Adequate knowledge about this relationship can potentially improve accuracy for ...
Wei Zhong, Jieyue He, Robert W. Harrison, Phang C....
BMCBI
2006
201views more  BMCBI 2006»
13 years 7 months ago
Gene selection algorithms for microarray data based on least squares support vector machine
Background: In discriminant analysis of microarray data, usually a small number of samples are expressed by a large number of genes. It is not only difficult but also unnecessary ...
E. Ke Tang, Ponnuthurai N. Suganthan, Xin Yao
TITB
2008
102views more  TITB 2008»
13 years 7 months ago
Nonlinear Support Vector Machine Visualization for Risk Factor Analysis Using Nomograms and Localized Radial Basis Function Kern
Nonlinear classifiers, e.g., support vector machines (SVMs) with radial basis function (RBF) kernels, have been used widely for automatic diagnosis of diseases because of their hig...
Baek Hwan Cho, Hwanjo Yu, Jong Shill Lee, Young Jo...