Background: Cancer diagnosis and clinical outcome prediction are among the most important emerging applications of gene expression microarray technology with several molecular sig...
Alexander R. Statnikov, Lily Wang, Constantin F. A...
Background: Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occur approximately every 1000 bases in the overall human population. The no...
Jian Tian, Ningfeng Wu, Xuexia Guo, Jun Guo, Juhua...
Understanding the sequence-to-structure relationship is a central task in bioinformatics research. Adequate knowledge about this relationship can potentially improve accuracy for ...
Wei Zhong, Jieyue He, Robert W. Harrison, Phang C....
Background: In discriminant analysis of microarray data, usually a small number of samples are expressed by a large number of genes. It is not only difficult but also unnecessary ...
Nonlinear classifiers, e.g., support vector machines (SVMs) with radial basis function (RBF) kernels, have been used widely for automatic diagnosis of diseases because of their hig...
Baek Hwan Cho, Hwanjo Yu, Jong Shill Lee, Young Jo...