5 search results - page 1 / 1 » Applying unmixing to gene expression data for tumor phylogen... |
BMCBI
2010
13 years 11 months ago
2010
Background: While in principle a seemingly infinite variety of combinations of mutations could result in tumor development, in practice it appears that most human cancers fall int...
BIOINFORMATICS
2010
13 years 11 months ago
2010
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
BMCBI
2005
13 years 11 months ago
2005
Background: Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to anal...
GPB
2010
13 years 8 months ago
2010
The detection of genes that show similar profiles under different experimental conditions is often an initial step in inferring the biological significance of such genes. Visualiz...
BMCBI
2010
13 years 6 months ago
2010
Background: The post-genomic era has brought new challenges regarding the understanding of the organization and function of the human genome. Many of these challenges are centered...