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» Approximate Global Alignment of Sequences
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RECOMB
2006
Springer
14 years 9 months ago
Alignment Statistics for Long-Range Correlated Genomic Sequences
It is well known that the base composition along eukaryotic genomes is long-range correlated. Here, we investigate the effect of such long-range correlations on alignment score sta...
Philipp W. Messer, Ralf Bundschuh, Martin Vingron,...
AAAI
2004
13 years 10 months ago
PROBCONS: Probabilistic Consistency-Based Multiple Alignment of Amino Acid Sequences
Obtaining an accurate multiple alignment of protein sequences is a difficult computational problem for which many heuristic techniques sacrifice optimality to achieve reasonable r...
Chuong B. Do, Michael Brudno, Serafim Batzoglou
BMCBI
2005
132views more  BMCBI 2005»
13 years 8 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer
DATESO
2007
157views Database» more  DATESO 2007»
13 years 10 months ago
Index-Based Approach to Similarity Search in Protein and Nucleotide Databases
When searching databases of nucleotide or protein sequences, finding a local alignment of two sequences is one of the main tasks. Since the sizes of available databases grow const...
David Hoksza, Tomás Skopal
DEXA
2007
Springer
150views Database» more  DEXA 2007»
14 years 2 months ago
Sequence Alignment as a Database Technology Challenge
Abstract. Sequence alignment is an important task for molecular biologists. Because alignment basically deals with approximate string matching on large biological sequence collecti...
Hans Philippi