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ALMOB
2008
95views more  ALMOB 2008»
15 years 2 months ago
A stitch in time: Efficient computation of genomic DNA melting bubbles
Background: It is of biological interest to make genome-wide predictions of the locations of DNA melting bubbles using statistical mechanics models. Computationally, this poses th...
Eivind Tøstesen
BMCBI
2010
178views more  BMCBI 2010»
15 years 2 months ago
Selecting high-dimensional mixed graphical models using minimal AIC or BIC forests
Background: Chow and Liu showed that the maximum likelihood tree for multivariate discrete distributions may be found using a maximum weight spanning tree algorithm, for example K...
David Edwards, Gabriel C. G. de Abreu, Rodrigo Lab...
135
Voted
BMCBI
2010
89views more  BMCBI 2010»
15 years 2 months ago
Predictors of natively unfolded proteins: unanimous consensus score to detect a twilight zone between order and disorder in gene
Background: Natively unfolded proteins lack a well defined three dimensional structure but have important biological functions, suggesting a re-assignment of the structure-functio...
Antonio Deiana, Andrea Giansanti
BMCBI
2007
104views more  BMCBI 2007»
15 years 2 months ago
Predicting active site residue annotations in the Pfam database
Background: Approximately 5% of Pfam families are enzymatic, but only a small fraction of the sequences within these families (<0.5%) have had the residues responsible for cata...
Jaina Mistry, Alex Bateman, Robert D. Finn
BMCBI
2008
132views more  BMCBI 2008»
15 years 2 months ago
Computational cluster validation for microarray data analysis: experimental assessment of Clest, Consensus Clustering, Figure of
Background: Inferring cluster structure in microarray datasets is a fundamental task for the so-called -omic sciences. It is also a fundamental question in Statistics, Data Analys...
Raffaele Giancarlo, Davide Scaturro, Filippo Utro
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