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» Are we Overestimating the Number of Cell-Cycling Genes
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BMCBI
2006
122views more  BMCBI 2006»
13 years 9 months ago
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
BMCBI
2008
146views more  BMCBI 2008»
13 years 9 months ago
A phase synchronization clustering algorithm for identifying interesting groups of genes from cell cycle expression data
Background: The previous studies of genome-wide expression patterns show that a certain percentage of genes are cell cycle regulated. The expression data has been analyzed in a nu...
Chang Sik Kim, Cheol Soo Bae, Hong Joon Tcha
BMCBI
2011
13 years 17 days ago
Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in Bre
Background: Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biologi...
Hiroko K. Solvang, Ole Christian Lingjærde, ...
BIOCOMP
2008
13 years 10 months ago
Reverse Engineering Module Networks by PSO-RNN Hybrid Modeling
Background: Inferring a gene regulatory network (GRN) from high throughput biological data is often an under-determined problem and is a challenging task due to the following reas...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...