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2006
Springer
13 years 11 months ago
Robust SVM-Based Biomarker Selection with Noisy Mass Spectrometric Proteomic Data
Abstract. Computational analysis of mass spectrometric (MS) proteomic data from sera is of potential relevance for diagnosis, prognosis, choice of therapy, and study of disease act...
Elena Marchiori, Connie R. Jimenez, Mikkel West-Ni...
BMCBI
2010
108views more  BMCBI 2010»
13 years 8 months ago
Predicting changes in protein thermostability brought about by single- or multi-site mutations
Background: An important aspect of protein design is the ability to predict changes in protein thermostability arising from single- or multi-site mutations. Protein thermostabilit...
Jian Tian, Ningfeng Wu, Xiaoyu Chu, Yunliu Fan
BMCBI
2008
170views more  BMCBI 2008»
13 years 8 months ago
A genetic approach for building different alphabets for peptide and protein classification
Background: In this paper, it is proposed an optimization approach for producing reduced alphabets for peptide classification, using a Genetic Algorithm. The classification task i...
Loris Nanni, Alessandra Lumini
BMCBI
2007
173views more  BMCBI 2007»
13 years 7 months ago
Recursive Cluster Elimination (RCE) for classification and feature selection from gene expression data
Background: Classification studies using gene expression datasets are usually based on small numbers of samples and tens of thousands of genes. The selection of those genes that a...
Malik Yousef, Segun Jung, Louise C. Showe, Michael...
ICIP
2008
IEEE
14 years 9 months ago
Supervised image segmentation via ground truth decomposition
This paper proposes a data driven image segmentation algorithm, based on decomposing the target output (ground truth). Classical pixel labeling methods utilize machine learning al...
Ilya Levner, Russell Greiner, Hong Zhang