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BMCBI
2011
12 years 11 months ago
Wavelet-based identification of DNA focal genomic aberrations from single nucleotide polymorphism arrays
Background: Copy number aberrations (CNAs) are an important molecular signature in cancer initiation, development, and progression. However, these aberrations span a wide range of...
Youngmi Hur, Hyunju Lee
BMCBI
2011
12 years 11 months ago
Assessing the functional coherence of modules found in multiple-evidence networks from Arabidopsis
Background: Combining multiple evidence-types from different information sources has the potential to reveal new relationships in biological systems. The integrated information ca...
Artem Lysenko, Michael Defoin-Platel, Keywan Hassa...
BMCBI
2011
12 years 11 months ago
Protein alignment algorithms with an efficient backtracking routine on multiple GPUs
Background: Pairwise sequence alignment methods are widely used in biological research. The increasing number of sequences is perceived as one of the upcoming challenges for seque...
Jacek Blazewicz, Wojciech Frohmberg, Michal Kierzy...
BMCBI
2011
12 years 11 months ago
Inference of Chromosome-Specific Copy Numbers Using Population Haplotypes
Background: Using microarray and sequencing platforms, a large number of copy number variations (CNVs) have been identified in humans. In practice, because our human genome is a d...
Yao-Ting Huang, Min-Han Wu
BMCBI
2011
12 years 11 months ago
MINE: Module Identification in NEtworks
Background: Graphical models of network associations are useful for both visualizing and integrating multiple types of association data. Identifying modules, or groups of function...
Kahn Rhrissorrakrai, Kristin C. Gunsalus
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