Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
Background: In the analysis of microarray data one generally produces a vector of p-values that for each gene give the likelihood of obtaining equally strong evidence of change by...
Many feature selection algorithms have been proposed in the past focusing on improving classification accuracy. In this work, we point out the importance of stable feature selecti...
Abstract. Gene expression profiling strategies have attracted considerable interest from biologist due to the potential for high throughput analysis of hundreds of thousands of gen...
Background: The availability of microarrays measuring thousands of genes simultaneously across hundreds of biological conditions represents an opportunity to understand both indiv...
Curtis Huttenhower, Avi I. Flamholz, Jessica N. La...