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» Assessment and Management of Single Nucleotide Polymorphism ...
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BMCBI
2006
97views more  BMCBI 2006»
13 years 7 months ago
PDA: Pooled DNA analyzer
Background: Association mapping using abundant single nucleotide polymorphisms is a powerful tool for identifying disease susceptibility genes for complex traits and exploring pos...
Hsin-Chou Yang, Chia-Ching Pan, Chin-Yu Lin, Cathy...
JCB
2008
94views more  JCB 2008»
13 years 7 months ago
Prioritize and Select SNPs for Association Studies with Multi-Stage Designs
Large-scale whole genome association studies are increasingly common, due in large part to recent advances in genotyping technology. With this change in paradigm for genetic studi...
Jing Li
RECOMB
2003
Springer
14 years 7 months ago
Large scale reconstruction of haplotypes from genotype data
Critical to the understanding of the genetic basis for complex diseases is the modeling of human variation. Most of this variation can be characterized by single nucleotide polymo...
Eleazar Eskin, Eran Halperin, Richard M. Karp
CIKM
2008
Springer
13 years 9 months ago
Viability of in-house datamarting approaches for population genetics analysis of snp genotypes
Background: Databases containing very large amounts of SNP (Single Nucleotide Polymorphism) data are now freely available for researchers interested in medical and/or population g...
Jorge Amigo, Christopher Phillips, Antonio Salas
RECOMB
2009
Springer
14 years 8 months ago
COE: A General Approach for Efficient Genome-Wide Two-Locus Epistasis Test in Disease Association Study
The availability of high density single nucleotide polymorphisms (SNPs) data has made genome-wide association study computationally challenging. Twolocus epistasis (gene-gene inter...
Xiang Zhang, Feng Pan, Yuying Xie, Fei Zou, Wei Wa...