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» Assessment and Management of Single Nucleotide Polymorphism ...
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BMCBI
2010
105views more  BMCBI 2010»
13 years 7 months ago
GWAMA: software for genome-wide association meta-analysis
Background: Despite the recent success of genome-wide association studies in identifying novel loci contributing effects to complex human traits, such as type 2 diabetes and obesi...
Reedik Mägi, Andrew P. Morris
BMCBI
2006
142views more  BMCBI 2006»
13 years 7 months ago
PedGenie: an analysis approach for genetic association testing in extended pedigrees and genealogies of arbitrary size
Background: We present a general approach to perform association analyses in pedigrees of arbitrary size and structure, which also allows for a mixture of pedigree members and ind...
Kristina Allen-Brady, Jathine Wong, Nicola J. Camp
TCBB
2008
115views more  TCBB 2008»
13 years 7 months ago
Highly Scalable Genotype Phasing by Entropy Minimization
A Single Nucleotide Polymorphism (SNP) is a position in the genome at which two or more of the possible four nucleotides occur in a large percentage of the population. SNPs accoun...
Alexander Gusev, Ion I. Mandoiu, Bogdan Pasaniuc
BMCBI
2006
135views more  BMCBI 2006»
13 years 7 months ago
iHAP - integrated haplotype analysis pipeline for characterizing the haplotype structure of genes
Background: The advent of genotype data from large-scale efforts that catalog the genetic variants of different populations have given rise to new avenues for multifactorial disea...
Chun Meng Song, Boon Huat Yeo, Erwin Tantoso, Yuch...
BMCBI
2008
111views more  BMCBI 2008»
13 years 7 months ago
SimHap GUI: An intuitive graphical user interface for genetic association analysis
Background: Researchers wishing to conduct genetic association analysis involving single nucleotide polymorphisms (SNPs) or haplotypes are often confronted with the lack of user-f...
Kim W. Carter, Pamela A. McCaskie, Lyle J. Palmer