181 search results - page 3 / 37 » Assessment of protein set coherence using functional annotat... |
BMCBI
2010
13 years 7 months ago
2010
Background: Analyzing interaction networks for functional characterization poses significant challenges arising from the noisy, incomplete, and generic nature of both the interact...
BMCBI
2005
13 years 7 months ago
2005
Background: The Gene Ontology Annotation (GOA) database http://www.ebi.ac.uk/GOA aims to provide high-quality supplementary GO annotation to proteins in the UniProt Knowledgebase....
BMCBI
2007
13 years 7 months ago
2007
Background: Incorrectly annotated sequence data are becoming more commonplace as databases increasingly rely on automated techniques for annotation. Hence, there is an urgent need...
BMCBI
2007
13 years 7 months ago
2007
Background: A widely-used approach for discovering functional and physical interactions among proteins involves phylogenetic profile comparisons (PPCs). Here, proteins with simila...
BMCBI
2005
13 years 7 months ago
2005
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...