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BMCBI
2007
104views more  BMCBI 2007»
13 years 7 months ago
Predicting active site residue annotations in the Pfam database
Background: Approximately 5% of Pfam families are enzymatic, but only a small fraction of the sequences within these families (<0.5%) have had the residues responsible for cata...
Jaina Mistry, Alex Bateman, Robert D. Finn
BMCBI
2008
101views more  BMCBI 2008»
13 years 7 months ago
Reranking candidate gene models with cross-species comparison for improved gene prediction
Background: Most gene finders score candidate gene models with state-based methods, typically HMMs, by combining local properties (coding potential, splice donor and acceptor patt...
Qian Liu, Koby Crammer, Fernando C. N. Pereira, Da...
BMCBI
2008
158views more  BMCBI 2008»
13 years 7 months ago
VarDetect: a nucleotide sequence variation exploratory tool
Background: Single nucleotide polymorphisms (SNPs) are the most commonly studied units of genetic variation. The discovery of such variation may help to identify causative gene mu...
Chumpol Ngamphiw, Supasak Kulawonganunchai, Anunch...
AML
2006
120views more  AML 2006»
13 years 7 months ago
On the infinite-valued Lukasiewicz logic that preserves degrees of truth
Lukasiewicz's infinite-valued logic is commonly defined as the set of formulas that take the value 1 under all evaluations in the Lukasiewicz algebra on the unit real interva...
Josep Maria Font, Àngel J. Gil, Antoni Torr...
BIOINFORMATICS
2006
142views more  BIOINFORMATICS 2006»
13 years 7 months ago
Intervention in a family of Boolean networks
Motivation: Intervention in a gene regulatory network is used to avoid undesirable states, such as those associated with a disease. Several types of intervention have been studied...
Ashish Choudhary, Aniruddha Datta, Michael L. Bitt...