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BMCBI
2010
115views more  BMCBI 2010»
13 years 9 months ago
Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
CIKM
2008
Springer
13 years 10 months ago
Passage relevance models for genomics search
We present a passage relevance model for integrating syntactic and semantic evidence of biomedical concepts and topics using a probabilistic graphical model. Component models of t...
Jay Urbain, Ophir Frieder, Nazli Goharian
BMCBI
2007
147views more  BMCBI 2007»
13 years 8 months ago
Modeling biochemical transformation processes and information processing with Narrator
Background: Software tools that model and simulate the dynamics of biological processes and systems are becoming increasingly important. Some of these tools offer sophisticated gr...
Johannes J. Mandel, Hendrik Fuß, Niall M. Pa...
BMCBI
2006
118views more  BMCBI 2006»
13 years 8 months ago
Djinn Lite: a tool for customised gene transcript modelling, annotation-data enrichment and exploration
Background: There is an ever increasing rate of data made available on genetic variation, transcriptomes and proteomes. Similarly, a growing variety of bioinformatic programs are ...
Erdahl T. Teber, Edward Crawford, Kent B. Bolton, ...
BMCBI
2011
13 years 11 days ago
Acorn: A grid computing system for constraint based modeling and visualization of the genome scale metabolic reaction networks v
Background: Constraint-based approaches facilitate the prediction of cellular metabolic capabilities, based, in turn on predictions of the repertoire of enzymes encoded in the gen...
Jacek Sroka, Lukasz Bieniasz-Krzywiec, Szymon Gwoz...