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» Automated Extraction of Problem Structure
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BMCBI
2006
120views more  BMCBI 2006»
13 years 9 months ago
Integrating protein structures and precomputed genealogies in the Magnum database: Examples with cellular retinoid binding prote
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...
Michael E. Bradley, Steven A. Benner
BMCBI
2007
134views more  BMCBI 2007»
13 years 9 months ago
Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign
Background: Joint alignment and secondary structure prediction of two RNA sequences can significantly improve the accuracy of the structural predictions. Methods addressing this p...
Arif Ozgun Harmanci, Gaurav Sharma, David H. Mathe...
CSB
2005
IEEE
136views Bioinformatics» more  CSB 2005»
14 years 2 months ago
An Algebraic Geometry Approach to Protein Structure Determination from NMR Data
Our paper describes the first provably-efficient algorithm for determining protein structures de novo, solely from experimental data. We show how the global nature of a certain ...
Lincong Wang, Ramgopal R. Mettu, Bruce Randall Don...
WIDM
2003
ACM
14 years 2 months ago
Conceptual modeling of semantic navigation structures: the MoSeNa-approach
At the present time, several shortcomings prevent the more effective use and more intense application of web information systems. Recent developments that are subsumed by the term...
Jörg Becker, Christian Brelage, Karsten Klose...
ICDM
2005
IEEE
125views Data Mining» more  ICDM 2005»
14 years 2 months ago
Alternate Representation of Distance Matrices for Characterization of Protein Structure
The most suitable method for the automated classification of protein structures remains an open problem in computational biology. In order to classify a protein structure with an...
Keith Marsolo, Srinivasan Parthasarathy