While a typical software component has a clearly specified (static) interface in terms of the methods and the input/output types they support, information about the correct sequen...
Identification of the short DNA sequence motifs that serve as binding targets for transcription factors is an important challenge in bioinformatics. Unsupervised techniques from t...
Shaun Mahony, Panayiotis V. Benos, Terry J. Smith,...
The problem of tracking a varying number of non-rigid objects has two major difficulties. First, the observation models and target distributions can be highly non-linear and non-Ga...
Kenji Okuma, Ali Taleghani, Nando de Freitas, Jame...
Existing query interfaces for biological databases are either based on fixed forms or textual query languages. Users of a fixed form-based query interface are limited to performin...
I-Min A. Chen, Anthony Kosky, Victor M. Markowitz,...
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...