Background: In recent years, mammalian protein-protein interaction network databases have been developed. The interactions in these databases are either extracted manually from lo...
Background: Benchmarking algorithms in structural bioinformatics often involves the construction of datasets of proteins with given sequence and structural properties. The SCOP da...
James A. Casbon, Gavin E. Crooks, Mansoor A. S. Sa...
Background: Detection of Loss of Heterozygosity (LOH) is one of the most common molecular applications in the study of human diseases, in particular cancer. The technique is commo...
Nonlinear classifiers, e.g., support vector machines (SVMs) with radial basis function (RBF) kernels, have been used widely for automatic diagnosis of diseases because of their hig...
Baek Hwan Cho, Hwanjo Yu, Jong Shill Lee, Young Jo...
Background: Genome wide microarray studies have the potential to unveil novel disease entities. Clinically homogeneous groups of patients can have diverse gene expression profiles...