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BMCBI
2006
182views more  BMCBI 2006»
13 years 8 months ago
AceTree: a tool for visual analysis of Caenorhabditis elegans embryogenesis
Background: The invariant lineage of the nematode Caenorhabditis elegans has potential as a powerful tool for the description of mutant phenotypes and gene expression patterns. We...
Thomas J. Boyle, Zhirong Bao, John I. Murray, Carl...
BMCBI
2006
154views more  BMCBI 2006»
13 years 8 months ago
Agile methods in biomedical software development: a multi-site experience report
Background: Agile is an iterative approach to software development that relies on strong collaboration and automation to keep pace with dynamic environments. We have successfully ...
David W. Kane, Moses M. Hohman, Ethan G. Cerami, M...
BMCBI
2007
94views more  BMCBI 2007»
13 years 8 months ago
Model based analysis of real-time PCR data from DNA binding dye protocols
Background: Reverse transcription followed by real-time PCR is widely used for quantification of specific mRNA, and with the use of double-stranded DNA binding dyes it is becoming...
Mariano J. Alvarez, Guillermo J. Vila-Ortiz, Maria...
BMCBI
2007
102views more  BMCBI 2007»
13 years 8 months ago
Setting up a large set of protein-ligand PDB complexes for the development and validation of knowledge-based docking algorithms
Background: The number of algorithms available to predict ligand-protein interactions is large and ever-increasing. The number of test cases used to validate these methods is usua...
Luis A. Diago, Persy Morell, Longendri Aguilera, E...
BMCBI
2007
98views more  BMCBI 2007»
13 years 8 months ago
Evaluation of 3D-Jury on CASP7 models
Background: 3D-Jury, the structure prediction consensus method publicly available in the Meta Server http://meta.bioinfo.pl/, was evaluated using models gathered in the 7th round ...
László Kaján, Leszek Rychlews...