Background: Expressed sequence tag (EST) collections are composed of a high number of single-pass, redundant, partial sequences, which need to be processed, clustered, and annotat...
Background: High-throughput automated sequencing has enabled an exponential growth rate of sequencing data. This requires increasing sequence quality and reliability in order to a...
We present an efficient, fully automated algorithm to assemble ESTs into full-length cDNA sequences that represent the complete coding regions of a gene. Our EST clustering algori...
Arthur Grossman, Charles Hauser, Hilary J. Holz, J...
Background: Processing raw DNA sequence data is an especially challenging task for relatively small laboratories and core facilities that produce as many as 5000 or more DNA seque...
Chun Liang, Feng Sun, Haiming Wang, Junfeng Qu, Ro...
Background: Investigators in the biological sciences continue to exploit laboratory automation methods and have dramatically increased the rates at which they can generate data. I...
Michael C. Wendl, Scott Smith, Craig S. Pohl, Davi...