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BIOINFORMATICS
2011
13 years 21 days ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...
JIB
2006
220views more  JIB 2006»
13 years 9 months ago
An assessment of machine and statistical learning approaches to inferring networks of protein-protein interactions
Protein-protein interactions (PPI) play a key role in many biological systems. Over the past few years, an explosion in availability of functional biological data obtained from hi...
Fiona Browne, Haiying Wang, Huiru Zheng, Francisco...
BMCBI
2008
136views more  BMCBI 2008»
13 years 9 months ago
Allowing for mandatory covariates in boosting estimation of sparse high-dimensional survival models
Background: When predictive survival models are built from high-dimensional data, there are often additional covariates, such as clinical scores, that by all means have to be incl...
Harald Binder, Martin Schumacher
TPDS
2008
113views more  TPDS 2008»
13 years 9 months ago
Evaluating a High-Level Parallel Language (GpH) for Computational GRIDs
Computational Grids potentially offer low cost, readily available, and large-scale high-performance platforms. For the parallel execution of programs, however, computational GRIDs ...
Abdallah Al Zain, Philip W. Trinder, Greg Michaels...
ISPAN
2009
IEEE
14 years 3 months ago
High-Performance Cloud Computing: A View of Scientific Applications
— Scientific computing often requires the availability of a massive number of computers for performing large scale experiments. Traditionally, these needs have been addressed by ...
Christian Vecchiola, Suraj Pandey, Rajkumar Buyya