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BMCBI
2010
86views more  BMCBI 2010»
13 years 8 months ago
Reaction graph kernels predict EC numbers of unknown enzymatic reactions in plant secondary metabolism
Background: Understanding of secondary metabolic pathway in plant is essential for finding druggable candidate enzymes. However, there are many enzymes whose functions are not yet...
Hiroto Saigo, Masahiro Hattori, Hisashi Kashima, K...
PROMISE
2010
13 years 2 months ago
Defect cost flow model: a Bayesian network for predicting defect correction effort
Background. Software defect prediction has been one of the central topics of software engineering. Predicted defect counts have been used mainly to assess software quality and est...
Thomas Schulz, Lukasz Radlinski, Thomas Gorges, Wo...
BMCBI
2010
109views more  BMCBI 2010»
13 years 8 months ago
Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
Background: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a dist...
Andrew J. Bordner, Hans D. Mittelmann
BMCBI
2007
134views more  BMCBI 2007»
13 years 8 months ago
Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign
Background: Joint alignment and secondary structure prediction of two RNA sequences can significantly improve the accuracy of the structural predictions. Methods addressing this p...
Arif Ozgun Harmanci, Gaurav Sharma, David H. Mathe...
KDD
2010
ACM
272views Data Mining» more  KDD 2010»
14 years 3 hour ago
Beyond heuristics: learning to classify vulnerabilities and predict exploits
The security demands on modern system administration are enormous and getting worse. Chief among these demands, administrators must monitor the continual ongoing disclosure of sof...
Mehran Bozorgi, Lawrence K. Saul, Stefan Savage, G...