58 search results - page 11 / 12 » B-Splines for Genomic Signatures |
BMCBI
2006
13 years 7 months ago
2006
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
BMCBI
2011
13 years 2 months ago
2011
Background: Genome-wide expression signatures are emerging as potential marker for overall survival and disease recurrence risk as evidenced by recent commercialization of gene ex...
RECOMB
2008
Springer
14 years 7 months ago
2008
Springer
Understanding the variation of recombination rates across a given genome is crucial for disease gene mapping and for detecting signatures of selection, to name just a couple of app...
RECOMB
2003
Springer
14 years 7 months ago
2003
Springer
Protein sequence alignments are more reliable the shorter the evolutionary distance. Here, we align distantly related proteins using many closely spaced intermediate sequences as ...
BMCBI
2007
13 years 7 months ago
2007
Background: RNA metabolism, through 'combinatorial splicing', can generate enormous structural diversity in the proteome. Alternative domains may interact, however, with...