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» B-Splines for Genomic Signatures
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BMCBI
2010
160views more  BMCBI 2010»
13 years 7 months ago
Annotation of gene promoters by integrative data-mining of ChIP-seq Pol-II enrichment data
Background: Use of alternative gene promoters that drive widespread cell-type, tissue-type or developmental gene regulation in mammalian genomes is a common phenomenon. Chromatin ...
Ravi Gupta, Priyankara Wikramasinghe, Anirban Bhat...
ALMOB
2006
97views more  ALMOB 2006»
13 years 7 months ago
The approximability of the String Barcoding problem
The String Barcoding (SBC) problem, introduced by Rash and Gusfield (RECOMB, 2002), consists in finding a minimum set of substrings that can be used to distinguish between all mem...
Giuseppe Lancia, Romeo Rizzi
BIBE
2007
IEEE
129views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Statistial Analysis of nucleosome occupancy and histone modification data
Abstract-- In eukaryotic cells, genomic DNAs wrap around beadlike molecules, called nucleosomes, so as to pack more compactly in the nucleus of the cell. The nucleosome is made up ...
Guo-Cheng Yuan, Jun S. Liu
BMCBI
2008
144views more  BMCBI 2008»
13 years 7 months ago
Local conservation scores without a priori assumptions on neutral substitution rates
Background: Comparative genomics aims to detect signals of evolutionary conservation as an indicator of functional constraint. Surprisingly, results of the ENCODE project revealed...
Janis Dingel, Pavol Hanus, Niccolò Leonardi...
BMCBI
2010
111views more  BMCBI 2010»
13 years 7 months ago
Functional Analysis: Evaluation of Response Intensities - Tailoring ANOVA for Lists of Expression Subsets
Background: Microarray data is frequently used to characterize the expression profile of a whole genome and to compare the characteristics of that genome under several conditions....
Fabrice Berger, Bertrand De Meulder, Anthoula Gaig...