Background: Many dimeric protein complexes bind cooperatively to families of bipartite nucleic acid sequence elements, which consist of pairs of conserved half-site sequences sepa...
Background: Computing exact multipoint LOD scores for extended pedigrees rapidly becomes infeasible as the number of markers and untyped individuals increase. When markers are exc...
Cornelis A. Albers, Martijn A. R. Leisink, Hilbert...
Background: In Eukaryotic genomes, different features including genes are not uniformly distributed. The integration of annotation information and genomic position of functional D...
Alessandro Coppe, Gian Antonio Danieli, Stefania B...
Background: Serial Analysis of Gene Expression (SAGE) is a high-throughput method for inferring mRNA expression levels from the experimentally generated sequence based tags. Stand...
Michael A. Gilchrist, Hong Qin, Russell L. Zaretzk...
Background: We develop a Bayesian method based on MCMC for estimating the relative rates of pericentric and paracentric inversions from marker data from two species. The method al...