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BMCBI
2005
150views more  BMCBI 2005»
13 years 7 months ago
Discover protein sequence signatures from protein-protein interaction data
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...
Jianwen Fang, Ryan J. Haasl, Yinghua Dong, Gerald ...
BMCBI
2005
152views more  BMCBI 2005»
13 years 7 months ago
GeneKeyDB: A lightweight, gene-centric, relational database to support data mining environments
Background: The analysis of biological data is greatly enhanced by existing or emerging databases. Most existing databases, with few exceptions are not designed to easily support ...
S. A. Kirov, X. Peng, E. Baker, D. Schmoyer, B. Zh...
BMCBI
2005
122views more  BMCBI 2005»
13 years 7 months ago
FACT - a framework for the functional interpretation of high-throughput experiments
Background: Interpreting the results of high-throughput experiments, such as those obtained from DNA-microarrays, is an often time-consuming task due to the high number of data-po...
Felix Kokocinski, Nicolas Delhomme, Gunnar Wrobel,...
BMCBI
2005
132views more  BMCBI 2005»
13 years 7 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer
BMCBI
2005
151views more  BMCBI 2005»
13 years 7 months ago
stam - a Bioconductor compliant R package for structured analysis of microarray data
Background: Genome wide microarray studies have the potential to unveil novel disease entities. Clinically homogeneous groups of patients can have diverse gene expression profiles...
Claudio Lottaz, Rainer Spang