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BIOCOMP
2006
13 years 9 months ago
Evaluation of a Novel Metric for Quality Control in an RNA Interference High Throughput Screening Assay
The application of genome scale RNA interference (RNAi) relies on the development of high quality RNAi high throughput screening (HTS) assays. An important quality control (QC) ch...
Xiaohua Douglas Zhang, Amy S. Espeseth, Namjin Chu...
SODA
2003
ACM
142views Algorithms» more  SODA 2003»
13 years 9 months ago
The similarity metric
—A new class of distances appropriate for measuring similarity relations between sequences, say one type of similarity per distance, is studied. We propose a new “normalized in...
Ming Li, Xin Chen, Xin Li, Bin Ma, Paul M. B. Vit&...
ALGORITHMICA
2007
114views more  ALGORITHMICA 2007»
13 years 7 months ago
The Consecutive Ones Submatrix Problem for Sparse Matrices
A 0-1 matrix has the Consecutive Ones Property (C1P) if there is a permutation of its columns that leaves the 1’s consecutive in each row. The Consecutive Ones Submatrix (C1S) p...
Jinsong Tan, Louxin Zhang
BMCBI
2010
109views more  BMCBI 2010»
13 years 7 months ago
FPGA acceleration of the phylogenetic likelihood function for Bayesian MCMC inference methods
Background: Likelihood (ML)-based phylogenetic inference has become a popular method for estimating the evolutionary relationships among species based on genomic sequence data. Th...
Stephanie Zierke, Jason D. Bakos
BMCBI
2007
127views more  BMCBI 2007»
13 years 7 months ago
A Latent Variable Approach for Meta-Analysis of Gene Expression Data from Multiple Microarray Experiments
Background: With the explosion in data generated using microarray technology by different investigators working on similar experiments, it is of interest to combine results across...
Hyungwon Choi, Ronglai Shen, Arul M. Chinnaiyan, D...