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» Biclustering of Expression Data Using Simulated Annealing
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IJBRA
2007
89views more  IJBRA 2007»
13 years 8 months ago
Conservative adjustment of permutation p-values when the number of permutations is limited
The permutation procedure is widely used to assess the significance level (p-value) of a test statistic. This approach is asymptotically consistent. In genomics and proteomics st...
Yinglei Lai
CIBCB
2007
IEEE
14 years 18 days ago
Genetic Regulatory Network Modeling Using Network Component Analysis and Fuzzy Clustering
Gene regulatory network model is the most widely used mechanism to model and predict the behavior of living organisms. Network Component Analysis (NCA) as an emerging issue for unc...
Fatemeh Bakouie, Mohammad Hassan Moradi
BMCBI
2005
107views more  BMCBI 2005»
13 years 8 months ago
A stepwise framework for the normalization of array CGH data
Background: In two-channel competitive genomic hybridization microarray experiments, the ratio of the two fluorescent signal intensities at each spot on the microarray is commonly...
Mehrnoush Khojasteh, Wan L. Lam, Rabab Kreidieh Wa...
ICML
2009
IEEE
14 years 9 months ago
Group lasso with overlap and graph lasso
We propose a new penalty function which, when used as regularization for empirical risk minimization procedures, leads to sparse estimators. The support of the sparse vector is ty...
Laurent Jacob, Guillaume Obozinski, Jean-Philippe ...
BMCBI
2007
157views more  BMCBI 2007»
13 years 8 months ago
Improving gene set analysis of microarray data by SAM-GS
Background: Gene-set analysis evaluates the expression of biological pathways, or a priori defined gene sets, rather than that of individual genes, in association with a binary ph...
Irina Dinu, John D. Potter, Thomas Mueller, Qi Liu...