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BIOINFORMATICS
2011
12 years 11 months ago
ProDy: Protein Dynamics Inferred from Theory and Experiments
Summary: We developed a Python package, ProDy, for structurebased analysis of protein dynamics. ProDy allows for quantitative characterization of structural variations in heteroge...
Ahmet Bakan, Lidio M. Meireles, Ivet Bahar
FLAIRS
2008
13 years 10 months ago
Contrast Pattern Mining with Gap Constraints for Peptide Folding Prediction
1 In this paper, we propose a peptide folding prediction method which discovers contrast patterns to differentiate and predict peptide folding classes. A contrast pattern is defin...
Chinar C. Shah, Xingquan Zhu, Taghi M. Khoshgoftaa...
BMCBI
2010
118views more  BMCBI 2010»
13 years 8 months ago
Computing H/D-Exchange rates of single residues from data of proteolytic fragments
Background: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/ Deuterium exchange (sHDX) coupled to high-resolution mass analysis o...
Ernst Althaus, Stefan Canzar, Carsten Ehrler, Mark...
BMCBI
2010
116views more  BMCBI 2010»
13 years 8 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
CP
2003
Springer
14 years 1 months ago
Propagating N-Ary Rigid-Body Constraints
In this paper, we present an algorithm to propagate an n-ary constraint (with n greater than 2) specifying the relative positions of points in a three-dimensional rigid group. The ...
Ludwig Krippahl, Pedro Barahona