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» Binarized Support Vector Machines
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BMCBI
2006
126views more  BMCBI 2006»
13 years 10 months ago
A Regression-based K nearest neighbor algorithm for gene function prediction from heterogeneous data
Background: As a variety of functional genomic and proteomic techniques become available, there is an increasing need for functional analysis methodologies that integrate heteroge...
Zizhen Yao, Walter L. Ruzzo
BMCBI
2007
157views more  BMCBI 2007»
13 years 10 months ago
Statistical learning of peptide retention behavior in chromatographic separations: a new kernel-based approach for computational
Background: High-throughput peptide and protein identification technologies have benefited tremendously from strategies based on tandem mass spectrometry (MS/MS) in combination wi...
Nico Pfeifer, Andreas Leinenbach, Christian G. Hub...
BMCBI
2007
77views more  BMCBI 2007»
13 years 10 months ago
Effective selection of informative SNPs and classification on the HapMap genotype data
Background: Since the single nucleotide polymorphisms (SNPs) are genetic variations which determine the difference between any two unrelated individuals, the SNPs can be used to i...
Nina Zhou, Lipo Wang
BMCBI
2007
113views more  BMCBI 2007»
13 years 10 months ago
Analysis and prediction of antibacterial peptides
Background: Antibacterial peptides are important components of the innate immune system, used by the host to protect itself from different types of pathogenic bacteria. Over the l...
Sneh Lata, B. K. Sharma, G. P. S. Raghava
BMCBI
2007
144views more  BMCBI 2007»
13 years 10 months ago
Motif kernel generated by genetic programming improves remote homology and fold detection
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
Tony Håndstad, Arne J. H. Hestnes, Pål...