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BMCBI
2005
148views more  BMCBI 2005»
13 years 7 months ago
Nonparametric tests for differential gene expression and interaction effects in multi-factorial microarray experiments
Background: Numerous nonparametric approaches have been proposed in literature to detect differential gene expression in the setting of two user-defined groups. However, there is ...
Xin Gao, Peter X. K. Song
BMCBI
2006
123views more  BMCBI 2006»
13 years 7 months ago
Characterizing disease states from topological properties of transcriptional regulatory networks
Background: High throughput gene expression experiments yield large amounts of data that can augment our understanding of disease processes, in addition to classifying samples. He...
David Tuck, Harriet Kluger, Yuval Kluger
BMCBI
2008
122views more  BMCBI 2008»
13 years 7 months ago
Determining gene expression on a single pair of microarrays
Background: In microarray experiments the numbers of replicates are often limited due to factors such as cost, availability of sample or poor hybridization. There are currently fe...
Robert W. Reid, Anthony A. Fodor
BMCBI
2007
117views more  BMCBI 2007»
13 years 7 months ago
Application of a correlation correction factor in a microarray cross-platform reproducibility study
Background: Recent research examining cross-platform correlation of gene expression intensities has yielded mixed results. In this study, we demonstrate use of a correction factor...
Kellie J. Archer, Catherine I. Dumur, G. Scott Tay...
BMCBI
2010
179views more  BMCBI 2010»
13 years 2 months ago
Circadian signatures in rat liver: from gene expression to pathways
Background: Circadian rhythms are 24 hour oscillations in many behavioural, physiological, cellular and molecular processes that are controlled by an endogenous clock which is ent...
Meric A. Ovacik, Siddharth Sukumaran, Richard R. A...