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» Bioinformatics Data Profiling Tools: A Prelude to Metabolic ...
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BMCBI
2008
77views more  BMCBI 2008»
13 years 10 months ago
SeqAn An efficient, generic C++ library for sequence analysis
Background: The use of novel algorithmic techniques is pivotal to many important problems in life science. For example the sequencing of the human genome [1] would not have been p...
Andreas Döring, David Weese, Tobias Rausch, K...
BMCBI
2004
228views more  BMCBI 2004»
13 years 9 months ago
An XML standard for the dissemination of annotated 2D gel electrophoresis data complemented with mass spectrometry results
Background: Many proteomics initiatives require a seamless bioinformatics integration of a range of analytical steps between sample collection and systems modeling immediately ass...
Romesh Stanislaus, Liu Hong Jiang, Martha Swartz, ...
BMCBI
2007
123views more  BMCBI 2007»
13 years 10 months ago
Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
Zailong Wang, Pearlly Yan, Dustin P. Potter, Chari...
BMCBI
2006
126views more  BMCBI 2006»
13 years 9 months ago
JUICE: a data management system that facilitates the analysis of large volumes of information in an EST project workflow
Background: Expressed sequence tag (EST) analyses provide a rapid and economical means to identify candidate genes that may be involved in a particular biological process. These E...
Mariano Latorre, Herman Silva, Juan Saba, Carito G...
BMCBI
2007
163views more  BMCBI 2007»
13 years 9 months ago
Use of genomic DNA control features and predicted operon structure in microarray data analysis: ArrayLeaRNA - a Bayesian approac
Background: Microarrays are widely used for the study of gene expression; however deciding on whether observed differences in expression are significant remains a challenge. Resul...
Carmen Pin, Mark Reuter