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» Biological information as set-based complexity
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RECOMB
2005
Springer
14 years 10 months ago
Predicting Protein-Peptide Binding Affinity by Learning Peptide-Peptide Distance Functions
Many important cellular response mechanisms are activated when a peptide binds to an appropriate receptor. In the immune system, the recognition of pathogen peptides begins when th...
Chen Yanover, Tomer Hertz
CMSB
2007
Springer
14 years 4 months ago
Expressive Models for Synaptic Plasticity
We explore some presynaptic mechanisms of the calyx of Held synapse through a stochastic model. The model, drawn from a kinetic approach developed in literature, exploits process c...
Andrea Bracciali, Marcello Brunelli, Enrico Catald...
HPDC
2010
IEEE
13 years 11 months ago
Biocompute: towards a collaborative workspace for data intensive bio-science
The explosion of data in the biological community demands the development of more scalable and flexible portals for bioinformatic computation. To address this need, we put forth c...
Rory Carmichael, Patrick Braga-Henebry, Douglas Th...
ALMOB
2008
112views more  ALMOB 2008»
13 years 10 months ago
Metabolite-based clustering and visualization of mass spectrometry data using one-dimensional self-organizing maps
Background: One of the goals of global metabolomic analysis is to identify metabolic markers that are hidden within a large background of data originating from high-throughput ana...
Peter Meinicke, Thomas Lingner, Alexander Kaever, ...
BMCBI
2010
133views more  BMCBI 2010»
13 years 10 months ago
New components of the Dictyostelium PKA pathway revealed by Bayesian analysis of expression data
Background: Identifying candidate genes in genetic networks is important for understanding regulation and biological function. Large gene expression datasets contain relevant info...
Anup Parikh, Eryong Huang, Christopher Dinh, Blaz ...