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» Biological information as set-based complexity
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BMCBI
2008
142views more  BMCBI 2008»
13 years 10 months ago
Strategies for measuring evolutionary conservation of RNA secondary structures
Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
Andreas R. Gruber, Stephan H. F. Bernhart, Ivo L. ...
BMCBI
2008
140views more  BMCBI 2008»
13 years 10 months ago
GORouter: an RDF model for providing semantic query and inference services for Gene Ontology and its associations
Background: The most renowned biological ontology, Gene Ontology (GO) is widely used for annotations of genes and gene products of different organisms. However, there are shortcom...
Qingwei Xu, Yixiang Shi, Qiang Lu, Guo-qing Zhang,...
BMCBI
2007
207views more  BMCBI 2007»
13 years 10 months ago
Analyzing in situ gene expression in the mouse brain with image registration, feature extraction and block clustering
Background: Many important high throughput projects use in situ hybridization and may require the analysis of images of spatial cross sections of organisms taken with cellular lev...
Manjunatha Jagalur, Chris Pal, Erik G. Learned-Mil...
JCB
2008
91views more  JCB 2008»
13 years 10 months ago
Computational Quantification of Peptides from LC-MS Data
Liquid chromatography coupled to mass spectrometry (LC-MS) has become a major tool for the study of biological processes. High-throughput LC-MS experiments are frequently conducte...
Ole Schulz-Trieglaff, Rene Hussong, Clemens Gr&oum...
CEC
2010
IEEE
13 years 5 months ago
Parameter estimation with term-wise decomposition in biochemical network GMA models by hybrid regularized Least Squares-Particle
High-throughput analytical techniques such as nuclear magnetic resonance, protein kinase phosphorylation, and mass spectroscopic methods generate time dense profiles of metabolites...
Prospero C. Naval, Luis G. Sison, Eduardo R. Mendo...