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    BMCBI
    2006
    239views more  BMCBI 2006»
    Applying dynamic Bayesian networks to perturbed gene expression data
    13 years 10 months ago
    Applying dynamic Bayesian networks to perturbed gene expression data
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    Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
    Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
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    BMCBI
    2006
    158views more  BMCBI 2006»
    Parallelization of multicategory support vector machines (PMC-SVM) for classifying microarray data
    13 years 10 months ago
    Parallelization of multicategory support vector machines (PMC-SVM) for classifying microarray data
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    Background: Multicategory Support Vector Machines (MC-SVM) are powerful classification systems with excellent performance in a variety of data classification problems. Since the p...
    Chaoyang Zhang, Peng Li, Arun Rajendran, Youping D...
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    BMCBI
    2006
    130views more  BMCBI 2006»
    An accurate and interpretable model for siRNA efficacy prediction
    13 years 10 months ago
    An accurate and interpretable model for siRNA efficacy prediction
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    Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
    Jean-Philippe Vert, Nicolas Foveau, Christian Laja...
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    BMCBI
    2007
    138views more  BMCBI 2007»
    A novel Bayesian approach to quantify clinical variables and to determine their spectroscopic counterparts in 1H NMR metabonomic
    13 years 10 months ago
    A novel Bayesian approach to quantify clinical variables and to determine their spectroscopic counterparts in 1H NMR metabonomic
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    Background: A key challenge in metabonomics is to uncover quantitative associations between multidimensional spectroscopic data and biochemical measures used for disease risk asse...
    Aki Vehtari, Ville-Petteri Mäkinen, Pasi Soin...
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    JIB
    2006
    106views more  JIB 2006»
    A structural keystone for drug design
    13 years 10 months ago
    A structural keystone for drug design
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    3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether b...
    Kristian Rother, Mathias Dunkel, Elke Michalsky, S...
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