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» BiologicalNetworks 2.0 - an integrative view of genome biolo...
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BMCBI
2007
126views more  BMCBI 2007»
13 years 7 months ago
Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...
BMCBI
2007
111views more  BMCBI 2007»
13 years 7 months ago
Modular co-evolution of metabolic networks
Background: The architecture of biological networks has been reported to exhibit high level of modularity, and to some extent, topological modules of networks overlap with known f...
Jing Zhao, Guohui Ding, Lin Tao, Hong Yu, Zhong-Ha...
BIOINFORMATICS
2002
146views more  BIOINFORMATICS 2002»
13 years 7 months ago
A duplication growth model of gene expression networks
Motivation: There has been considerable interest in developing computational techniques for inferring genetic regulatory networks from whole-genome expression profiles. When expre...
Ashish Bhan, David J. Galas, T. Gregory Dewey
IJKDB
2010
170views more  IJKDB 2010»
13 years 4 months ago
Clustering Genes Using Heterogeneous Data Sources
Clustering of gene expression data is a standard exploratory technique used to identify closely related genes. Many other sources of data are also likely to be of great assistance...
Erliang Zeng, Chengyong Yang, Tao Li, Giri Narasim...
CBMS
2004
IEEE
13 years 11 months ago
Toward a Systems Biology Software Toolkit
Insight to complex problems may be revealed when domain data sets are viewed or structured in new and innovative ways. Systems approaches to biomedical problems fundamentally invo...
Donald J. Johann, Michael D. McGuigan, Stanimire T...