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» Biomedical Hypothesis Generation and Testing by Evolutionary...
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BMCBI
2007
120views more  BMCBI 2007»
13 years 7 months ago
Re-sampling strategy to improve the estimation of number of null hypotheses in FDR control under strong correlation structures
Background: When conducting multiple hypothesis tests, it is important to control the number of false positives, or the False Discovery Rate (FDR). However, there is a tradeoff be...
Xin Lu, David L. Perkins
UAI
2008
13 years 8 months ago
CT-NOR: Representing and Reasoning About Events in Continuous Time
We present a generative model for representing and reasoning about the relationships among events in continuous time. We apply the model to the domain of networked and distributed...
Aleksandr Simma, Moisés Goldszmidt, John Ma...
EVOW
2006
Springer
13 years 11 months ago
Hierarchical Clustering, Languages and Cancer
In this paper, we introduce a novel objective function for the hierarchical clustering of data from distance matrices, a very relevant task in Bioinformatics. To test the robustnes...
Pritha Mahata, Wagner Costa, Carlos Cotta, Pablo M...
CEC
2009
IEEE
14 years 2 months ago
The multiobjective evolutionary algorithm based on determined weight and sub-regional search
— By dividing the multiobjective optimization of the decision space into several small regions, this paper proposes multi-objective optimization algorithm based on sub-regional s...
Hai-lin Liu, Xueqiang Li
BMCBI
2004
146views more  BMCBI 2004»
13 years 7 months ago
Multivariate search for differentially expressed gene combinations
Background: To identify differentially expressed genes, it is standard practice to test a twosample hypothesis for each gene with a proper adjustment for multiple testing. Such te...
Yuanhui Xiao, Robert D. Frisina, Alexander Gordon,...