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    BMCBI
    2010
    189views more  BMCBI 2010»
    High quality protein sequence alignment by combining structural profile prediction and profile alignment using SABERTOOTH
    13 years 9 months ago
    High quality protein sequence alignment by combining structural profile prediction and profile alignment using SABERTOOTH
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    Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...
    Florian Teichert, Jonas Minning, Ugo Bastolla, Mar...
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    BMCBI
    2010
    227views more  BMCBI 2010»
    Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usage
    13 years 9 months ago
    Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usage
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    Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
    Majid Masso, Iosif I. Vaisman
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    BMCBI
    2007
    168views more  BMCBI 2007»
    Benchmarking consensus model quality assessment for protein fold recognition
    13 years 9 months ago
    Benchmarking consensus model quality assessment for protein fold recognition
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    Background: Selecting the highest quality 3D model of a protein structure from a number of alternatives remains an important challenge in the field of structural bioinformatics. M...
    Liam J. McGuffin
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    BMCBI
    2008
    107views more  BMCBI 2008»
    A machine learning approach to explore the spectra intensity pattern of peptides using tandem mass spectrometry data
    13 years 9 months ago
    A machine learning approach to explore the spectra intensity pattern of peptides using tandem mass spectrometry data
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    Background: A better understanding of the mechanisms involved in gas-phase fragmentation of peptides is essential for the development of more reliable algorithms for high-throughp...
    Cong Zhou, Lucas D. Bowler, Jianfeng Feng
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    BMCBI
    2008
    134views more  BMCBI 2008»
    Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sites
    13 years 9 months ago
    Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sites
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    Background: Utilization of alternative initiation sites for protein translation directed by non-AUG codons in mammalian mRNAs is observed with increasing frequency. Alternative in...
    Jill L. Wegrzyn, Thomas M. Drudge, Faramarz Valafa...
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