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GECCO
2009
Springer
14 years 2 months ago
Multiobjectivization for parameter estimation: a case-study on the segment polarity network of drosophila
Mathematical modeling for gene regulative networks (GRNs) provides an effective tool for hypothesis testing in biology. A necessary step in setting up such models is the estimati...
Tim Hohm, Eckart Zitzler
BMCBI
2010
233views more  BMCBI 2010»
13 years 7 months ago
Odefy -- From discrete to continuous models
Background: Phenomenological information about regulatory interactions is frequently available and can be readily converted to Boolean models. Fully quantitative models, on the ot...
Jan Krumsiek, Sebastian Pölsterl, Dominik M. ...
ISCIS
2009
Springer
14 years 2 months ago
A web-based data source for metabolomics
—With the development of improved and cost-effective technologies, it is now possible to detect thousands of metabolites in biofluids or specific organs, and reliably quantify th...
Ali Cakmak, Arun Dsouza, Richard Hanson, Gultekin ...
BMCBI
2007
146views more  BMCBI 2007»
13 years 7 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
SDM
2012
SIAM
208views Data Mining» more  SDM 2012»
11 years 10 months ago
Mining Massive Archives of Mice Sounds with Symbolized Representations
Many animals produce long sequences of vocalizations best described as “songs.” In some animals, such as crickets and frogs, these songs are relatively simple and repetitive c...
Jesin Zakaria, Sarah Rotschafer, Abdullah Mueen, K...