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ESANN
2004
13 years 10 months ago
Sparse LS-SVMs using additive regularization with a penalized validation criterion
This paper is based on a new way for determining the regularization trade-off in least squares support vector machines (LS-SVMs) via a mechanism of additive regularization which ha...
Kristiaan Pelckmans, Johan A. K. Suykens, Bart De ...
BMCBI
2010
136views more  BMCBI 2010»
13 years 8 months ago
An integrated Bayesian analysis of LOH and copy number data
Background: Cancer and other disorders are due to genomic lesions. SNP-microarrays are able to measure simultaneously both genotype and copy number (CN) at several Single Nucleoti...
Paola M. V. Rancoita, Marcus Hutter, Francesco Ber...
BMCBI
2007
99views more  BMCBI 2007»
13 years 8 months ago
Orthogonal projections to latent structures as a strategy for microarray data normalization
Background: During generation of microarray data, various forms of systematic biases are frequently introduced which limits accuracy and precision of the results. In order to prop...
Max Bylesjö, Daniel Eriksson, Andreas Sjö...
CSDA
2008
128views more  CSDA 2008»
13 years 8 months ago
Classification tree analysis using TARGET
Tree models are valuable tools for predictive modeling and data mining. Traditional tree-growing methodologies such as CART are known to suffer from problems including greediness,...
J. Brian Gray, Guangzhe Fan
BMCBI
2006
240views more  BMCBI 2006»
13 years 8 months ago
Statistical analysis of real-time PCR data
Background: Even though real-time PCR has been broadly applied in biomedical sciences, data processing procedures for the analysis of quantitative real-time PCR are still lacking;...
Joshua S. Yuan, Ann Reed, Feng Chen, C. Neal Stewa...