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BMCBI
2010
154views more  BMCBI 2010»
15 years 2 months ago
Motif Enrichment Analysis: a unified framework and an evaluation on ChIP data
Background: A major goal of molecular biology is determining the mechanisms that control the transcription of genes. Motif Enrichment Analysis (MEA) seeks to determine which DNA-b...
Robert C. McLeay, Timothy L. Bailey
BMCBI
2006
190views more  BMCBI 2006»
15 years 2 months ago
VANTED: A system for advanced data analysis and visualization in the context of biological networks
Background: Recent advances with high-throughput methods in life-science research have increased the need for automatized data analysis and visual exploration techniques. Sophisti...
Björn H. Junker, Christian Klukas, Falk Schre...
BMCBI
2010
134views more  BMCBI 2010»
15 years 2 months ago
R-Gada: a fast and flexible pipeline for copy number analysis in association studies
Background: Genome-wide association studies (GWAS) using Copy Number Variation (CNV) are becoming a central focus of genetic research. CNVs have successfully provided target genom...
Roger Pique-Regi, Alejandro Cáceres, Juan R...
BMCBI
2004
150views more  BMCBI 2004»
15 years 2 months ago
Graph-based iterative Group Analysis enhances microarray interpretation
Background: One of the most time-consuming tasks after performing a gene expression experiment is the biological interpretation of the results by identifying physiologically impor...
Rainer Breitling, Anna Amtmann, Pawel Herzyk
WWW
2010
ACM
15 years 9 months ago
Sampling community structure
We propose a novel method, based on concepts from expander graphs, to sample communities in networks. We show that our sampling method, unlike previous techniques, produces subgra...
Arun S. Maiya, Tanya Y. Berger-Wolf