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BMCBI
2006
124views more  BMCBI 2006»
13 years 8 months ago
The development and validation of the Virtual Tissue Matrix, a software application that facilitates the review of tissue microa
Background: The Tissue Microarray (TMA) facilitates high-throughput analysis of hundreds of tissue specimens simultaneously. However, bottlenecks in the storage and manipulation o...
Catherine M. Conway, Deirdre O'Shea, Sallyann O'Br...
BMCBI
2006
91views more  BMCBI 2006»
13 years 8 months ago
PeanutMap: an online genome database for comparative molecular maps of peanut
Background: Molecular maps have been developed for many species, and are of particular importance for varietal development and comparative genomics. However, despite the existence...
Arun M. Jesubatham, Mark D. Burow
BMCBI
2006
127views more  BMCBI 2006»
13 years 8 months ago
Using local gene expression similarities to discover regulatory binding site modules
Background: We present an approach designed to identify gene regulation patterns using sequence and expression data collected for Saccharomyces cerevisae. Our main goal is to rela...
Bartek Wilczynski, Torgeir R. Hvidsten, Andriy Kry...
BMCBI
2006
130views more  BMCBI 2006»
13 years 8 months ago
An accurate and interpretable model for siRNA efficacy prediction
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
Jean-Philippe Vert, Nicolas Foveau, Christian Laja...
BMCBI
2006
82views more  BMCBI 2006»
13 years 8 months ago
Prediction of a key role of motifs binding E2F and NR2F in down-regulation of numerous genes during the development of the mouse
Background: We previously demonstrated that gene expression profiles during neuronal differentiation in vitro and hippocampal development in vivo were very similar, due to a conse...
Michal Dabrowski, Stein Aerts, Bozena Kaminska
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