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BMCBI
2010
116views more  BMCBI 2010»
13 years 10 months ago
A hybrid approach to protein folding problem integrating constraint programming with local search
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
Abu Zafer M. Dayem Ullah, Kathleen Steinhöfel
BMCBI
2007
105views more  BMCBI 2007»
13 years 10 months ago
Predicting RNA secondary structure by the comparative approach: how to select the homologous sequences
Background: The secondary structure of an RNA must be known before the relationship between its structure and function can be determined. One way to predict the secondary structur...
Stefan Engelen, Fariza Tahi
BMCBI
2007
128views more  BMCBI 2007»
13 years 10 months ago
A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand bindin
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
Lei Xie, Philip E. Bourne
BMCBI
2007
155views more  BMCBI 2007»
13 years 10 months ago
ProCMD: a database and 3D web resource for protein C mutants
Background: Activated Protein C (ProC) is an anticoagulant plasma serine protease which also plays an important role in controlling inflammation and cell proliferation. Several mu...
Pasqualina D'Ursi, Francesca Marino, Andrea Caprer...
GRID
2006
Springer
13 years 10 months ago
The Palantir Grid Meta-Information System
Grids allow large scale resource-sharing across different administrative domains. Those diverse resources are likely to join or quit the Grid at any moment or possibly to break dow...
Francesc Guim, Ivan Rodero, M. Tomas, Julita Corba...