Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
Jan Schellenberger, Junyoung O. Park, Tom M. Conra...
Background: Experimental studies of gene expression have identified some of the individual molecular components and elementary reactions that comprise and control cellular behavio...
We describe the informatics requirements of translational biomedical research projects and how e-Science tools can be used to address them. We use pattern templates to describe the...
Background: Serial Analysis of Gene Expressions (SAGE) produces gene expression measurements on a discrete scale, due to the finite number of molecules in the sample. This means t...
Background: Protein secondary structure prediction is a fundamental and important component in the analytical study of protein structure and functions. The prediction technique ha...