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BMCBI
2008
13 years 10 months ago
2008
Background: Advances in automated DNA sequencing technology have accelerated the generation of metagenomic DNA sequences, especially environmental ribosomal RNA gene (rDNA) sequen...
BMCBI
2008
13 years 10 months ago
2008
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
BMCBI
2010
13 years 10 months ago
2010
Background: Molecular interaction networks can be efficiently studied using network visualization software such as Cytoscape. The relevant nodes, edges and their attributes can be...
BMCBI
2007
13 years 10 months ago
2007
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
BMCBI
2010
13 years 10 months ago
2010
Background: Microarray experiments have become very popular in life science research. However, if such experiments are only considered independently, the possibilities for analysi...