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» Building Large Knowledge Bases in Molecular Biology
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BMCBI
2007
131views more  BMCBI 2007»
13 years 9 months ago
ISHAPE: new rapid and accurate software for haplotyping
Background: We have developed a new haplotyping program based on the combination of an iterative multiallelic EM algorithm (IEM), bootstrap resampling and a pseudo Gibbs sampler. ...
Olivier Delaneau, Cédric Coulonges, Pierre-...
BMCBI
2010
158views more  BMCBI 2010»
13 years 10 months ago
Validation of differential gene expression algorithms: Application comparing fold-change estimation to hypothesis testing
Background: Sustained research on the problem of determining which genes are differentially expressed on the basis of microarray data has yielded a plethora of statistical algorit...
Corey M. Yanofsky, David R. Bickel
BMCBI
2006
123views more  BMCBI 2006»
13 years 9 months ago
Computational models with thermodynamic and composition features improve siRNA design
Background: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large fun...
Svetlana A. Shabalina, Alexey N. Spiridonov, Aleks...
IANDC
2008
141views more  IANDC 2008»
13 years 9 months ago
Graph connectivity, partial words, and a theorem of Fine and Wilf
The problem of computing periods in words, or finite sequences of symbols from a finite alphabet, has important applications in several areas including data compression, string se...
Francine Blanchet-Sadri, Deepak Bal, Gautam Sisodi...
KDD
2004
ACM
137views Data Mining» more  KDD 2004»
14 years 3 months ago
Mining scale-free networks using geodesic clustering
Many real-world graphs have been shown to be scale-free— vertex degrees follow power law distributions, vertices tend to cluster, and the average length of all shortest paths is...
Andrew Y. Wu, Michael Garland, Jiawei Han