1018 search results - page 191 / 204 » Building the Biodiversity Commons |
155
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BMCBI
2007
15 years 4 months ago
2007
Background: Accurate sequence alignments are essential for homology searches and for building three-dimensional structural models of proteins. Since structure is better conserved ...
115
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BMCBI
2007
15 years 4 months ago
2007
Background: Protein domains coordinate to perform multifaceted cellular functions, and domain combinations serve as the functional building blocks of the cell. The available metho...
135
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BMCBI
2007
15 years 4 months ago
2007
Background: Experimentally determined protein structures may contain errors and require validation. Conformational criteria based on the Ramachandran plot are mainly used to disti...
157
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BMCBI
2008
15 years 4 months ago
2008
Background: The variety of DNA microarray formats and datasets presently available offers an unprecedented opportunity to perform insightful comparisons of heterogeneous data. Cro...
136
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BMCBI
2008
15 years 4 months ago
2008
Background The use of clustering methods for the discovery of cancer subtypes has drawn a great deal of attention in the scientific community. While bioinformaticians have propose...