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BMCBI
2007
147views more  BMCBI 2007»
13 years 10 months ago
Predicting combinatorial binding of transcription factors to regulatory elements in the human genome by association rule mining
Background: Cis-acting transcriptional regulatory elements in mammalian genomes typically contain specific combinations of binding sites for various transcription factors. Althoug...
Xochitl C. Morgan, Shulin Ni, Daniel P. Miranker, ...
CGF
2010
156views more  CGF 2010»
13 years 10 months ago
Mixed Finite Elements for Variational Surface Modeling
Many problems in geometric modeling can be described using variational formulations that define the smoothness of the shape and its behavior w.r.t. the posed modeling constraints....
Alec Jacobson, Elif Tosun, Olga Sorkine, Denis Zor...
BMCBI
2006
87views more  BMCBI 2006»
13 years 10 months ago
Phylogeny based discovery of regulatory elements
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...
Jason Gertz, Justin C. Fay, Barak A. Cohen
NAR
2007
132views more  NAR 2007»
13 years 9 months ago
TRED: a transcriptional regulatory element database, new entries and other development
Transcriptional factors (TFs) and many of their target genes are involved in gene regulation at the level of transcription. To decipher gene regulatory networks (GRNs) we require ...
C. Jiang, Zhenyu Xuan, Fang Zhao, Michael Q. Zhang
SIAMNUM
2010
95views more  SIAMNUM 2010»
13 years 4 months ago
Robust BDDC Preconditioners for Reissner-Mindlin Plate Bending Problems and MITC Elements
A Balancing Domain Decomposition Method by Constraints (BDDC) is constructed and analyzed for the Reissner-Mindlin plate bending problem discretized with MITC finite elements. This...
L. Beirão da Veiga, C. Chinosi, Carlo Lovad...