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CIBCB
2006
IEEE
14 years 1 months ago
E2D: A Novel Tool for Annotating Protein Domains in Expressed Sequence Tags
The vast number of expressed sequence tags (ESTs) in public databases provides an important resource for comparative and functional genomics. A variety of methods based on homology...
Guo-Hsing Lee, Nai-Yu Chuang, Wen-Dar Lin, Chung-D...
GCB
2010
Springer
122views Biometrics» more  GCB 2010»
13 years 5 months ago
Quantitative Comparison of Genomic-Wide Protein Domain Distributions
Abstract: Investigations into the origins and evolution of regulatory mechanisms require quantitative estimates of the abundance and co-occurrence of functional protein domains amo...
Arli A. Parikesit, Peter F. Stadler, Sonja J. Proh...
BMCBI
2007
141views more  BMCBI 2007»
13 years 7 months ago
Reconstruction of human protein interolog network using evolutionary conserved network
Background: The recent increase in the use of high-throughput two-hybrid analysis has generated large quantities of data on protein interactions. Specifically, the availability of...
Tao-Wei Huang, Chung-Yen Lin, Cheng-Yan Kao
NAR
2000
123views more  NAR 2000»
13 years 7 months ago
The Protein Information Resource (PIR)
The Protein Information Resource (PIR) produces the largest, most comprehensive, annotated protein sequence database in the public domain, the PIRInternational Protein Sequence Da...
Winona C. Barker, John S. Garavelli, Hongzhan Huan...
BMCBI
2007
113views more  BMCBI 2007»
13 years 7 months ago
Hinge Atlas: relating protein sequence to sites of structural flexibility
Background: Relating features of protein sequences to structural hinges is important for identifying domain boundaries, understanding structure-function relationships, and designi...
Samuel Flores, Long J. Lu, Julie Yang, Nicholas Ca...